Yes, though FedEx will allow you to do so only once. Options for administering the changes are as follows:
1) Reroute your package to a nearby FedEx or retail location where they’ll hold your package for five days at no additional cost in anticipation of your in-person pickup. Instructions – https://www.fedex.com/en-us/shipping/hold-at-location.html
2) Contact us to request an address change on your behalf. You’ll incur a $16 FedEx fee plus any applicable difference in the cost of shipping to the new destination, which will be charged to your credit card on file.